Webbie

"WebbIE is a web browser for blind and visually-impaired people, especially those using screen readers, used since 2001 all over the world. It comes with the Accessible programs, letting you access news and audio on the Internet in a simple and accessible way, allowing you to use podcasts, listen to the radio and read RSS and news with your screen reader or other access solution. Together they provide a way to access websites and other great things online - and they are all free! Learn more about WebbIE."

Anyone interested in accessibility issues should read their page about making accessible websites. It's a no nonsense guide and explains things really well. I give it 5 stars.